Details, Fiction and megatomi.com
Details, Fiction and megatomi.com
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Rapidly acquire sections as slim or thick as your software necessitates, without worrying about shedding or distorting important tissue samples.
Megatome is often a vibrating microtome built to section a wide range of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome enables large-throughput tissue sectioning with uniform floor profile, along with small tissue problems and knowledge decline.
Antibodies could get months to diffuse by only some millimeters of tissue, that has a steep labeling gradient from surface to Main.
Megatome is created for precision: the blade vibrates at an increased frequency and bigger amplitude selection than other microtomes, and incorporates a exclusive deflection Handle mechanism.
SE makes use of a rotational electric field to disperse really electromobile molecules (which include antibodies or surfactant micelles) in the course of a porous sample with no harmful electrically charged structures throughout the tissue. This permits 2-4 working day clearing of intact organs,
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Megatome is actually a novel microtome that allows for high-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue destruction and data loss.
It’s the perfect time to update your microtome to Megatome. With accurate substantial-frequency slicing for an unmatched selection of sample dimensions and types – from organoids and megatomi.com tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied programs.
Completely delipidate full mouse brains or comparably sized samples in just one working day with SmartBatch+, or in one 7 days with our passive clearing kit.
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Either download a launch or make a distribution zip as outlined above. Unzip the archive to some sought after locale.
Leverage the Very clear+ tissue clearing strategy, coupled with eFLASH and patented stochastic electrotransport technologies, to quickly obvious and label total organs. Vital highlights and features include things like:
Our novel Protect tissue preservation technique types intramolecular bonds making use of polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.